Russian Scientists Develop Chemical Compounds That Halt Tumor Growth by Freezing Cells

A scientific team from the Ural Federal University in Russia has successfully synthesized new chemical compounds capable of stopping the growth of malignant tumors by freezing the cell division process rather than immediately destroying the cells. This breakthrough paves the way for a new generation of safer and more targeted cancer drugs.

According to reports by RT Arabic, the researchers tested these compounds on brain cancer, bladder cancer, and lung cancer cells, as well as on healthy cells, according to an official statement from the university.

The results showed that one of the substances has a “cytostatic” effect, preventing tumor growth without killing the cells. This significantly reduces the severe side effects associated with conventional chemotherapy treatments, which often damage healthy tissues.

In this context, the scientists identified the CDK2 protein, responsible for regulating the cell cycle, as a primary target for these compounds, using computer-based modeling techniques.

Associate Professor Konstantin Savatiev noted that two of the synthesized compounds demonstrated high selectivity in targeting bladder cancer cells and glioblastoma, while preserving the integrity of human kidney cells.

These drugs are expected to enter the Russian market within 7 to 10 years, provided they successfully pass all stages of testing.