Researchers from the Faculty of Pharmacy at the University of Seville, Spain, in collaboration with a team led by Dr. Marina Ezcurra from the University of Kent, UK, have obtained promising results regarding phytoene, a carotenoid. Their study revealed that this compound can extend the lifespan of nematodes — model organisms commonly used in Alzheimer’s research — and help delay paralysis caused by the accumulation of amyloid plaques, a hallmark of this neurodegenerative disease.
The study was recently published, on July 31, in the specialized journal Antioxidants.
Carotenoids are widely distributed natural compounds that play multiple biological roles. From them are derived apocarotenoids, which also play an important part in plant growth and environmental adaptation. Moreover, carotenoids are responsible for the bright colors of many fruits and vegetables, while serving as an essential source of certain vitamins, such as vitamin A.
An increasing body of scientific evidence supports the idea that these compounds may provide significant health benefits. They have been associated with a potential ability to help prevent various chronic conditions, including cancers, cardiovascular diseases, skin and bone disorders, eye diseases, metabolic problems, as well as age-related cognitive decline.
