Researchers Warn About the Effects of Paracetamol on Heart Health

A recent American study revealed that low doses of paracetamol, typically considered “safe,” can impact heart health.

The American research team concluded tha taking analgesics, also known as acetaminophen, led to protein modifications in the cardiac tissues of mice.

Dr. Gabriela Rivera from the University of California, Davis, stated, “We discovered that regular use of acetaminophen at concentrations deemed safe, around 500 milligrams per day, causes changes in numerous signaling pathways within the heart. We expected two or three pathways to be affected, but we found over 20 different signaling pathways altered.”

She further added, “These results prompt me to consider using acetaminophen at the lowest effective dose and for the shortest duration possible.”

Dr. Rivera explained that while our bodies can generally eliminate toxins before they cause harm, it may be challenging for the body to keep up with consistently taking moderate to high doses over time. It’s important to note that this study was conducted on mice, and further research is needed in humans.

Previous research has also indicated that taking large quantities of paracetamol can pose risks to heart health.


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